Influence of the temperature during the larval stage of development on lifespan in Drosophila melanogaster

  • A. S. Karaman
  • A. M. Vaiserman
  • A. V. Pisaruk
  • N. M. Koshel
  • L. V. Mekhova
  • I. A. Kozeretska

Abstract

Aim. To study the influence of different temperatures on larval stage on the development duration and life expectancy of Drosophila melanogaster imago. Methods. The statistical significance of the indicators was determined by one-way ANOVA followed by Tukey HSD post-hoc tests to evaluate significance of differences between groups. Results. The development duration of imagoes significantly increased by 1.7 times when the developmental temperature decreased from 27.5 to 20.0°С. The average and maximum lifespan of the flies was maximum at a temperature of 22.5°С. The lifespan of fruit flies was significantly decreased compared to control (25.0°С) at a developmental temperature of 20.0°C and above 22.5°C. Conclusions. The obtained data suggest that developmental temperature significantly affects the lifespan of the flies. It likely is a physiological optimum of the temperature of development, in which life expectancy is maximal. Probably, this is due to the fact that at optimal temperature, the Drosophila development is most complete and their viability is highest.
Keywords: Drosophila melanogaster, development, lifespan, temperature, larval stage.

References

Vaiserman A.M. Epigenetic programming by early-life stress: Evidence from human populations. Dev. Dyn. 2015a. 244, No. 3. P. 254–265. doi: 10.1002/dvdy.24211.

Vaiserman A.M. Epidemiologic evidence for association between adverse environmental exposures in early life and epigenetic variation: a potential link to disease susceptibility? Clin. Epigenetics. 2015. 7 (1). P. 96. doi: 10.1186/s13148-015-0130-0.

Vaiserman A.M., Koljada A.K., Zabuga O.G. Effect of Dietary Restriction during Development on the Level of Expression of Longevity-Associated Genes in Drosophila melanogaster. Advances in Gerontology. 2014. Vol. 4, No. 3. P. 193–196. doi: 10.1134/S2079057014030096.

Zwaan B.J., Bijlsma R., Hoekstra R.F. On the developmental theory of ageing. I. Starvation resistance and longevity in Drosophila melanogaster in relation to pre-adult breeding conditions. Heredity (Edinb). 1991. 66. (Pt 1). P. 29–39. doi: 10.1038/hdy.1991.4.

Lints F.A. Genetics and ageing. Interdisciplinary topics in gerontology. Basel. New York: Karger. 1978. Vol. 14. P. 3–58. doi: 10.1159/000402121.

Economos A.C., Lints F.A. Growth rate and life span in Drosophila. II. A biphasic relationship between growth rate and life span. Mech. Ageing Dev. 1984. Vol. 27, No. 2. P. 143–151. doi: 10.1016/0047-6374(84)90039-3.

Economos A.C., Lints F.A. Growth rate and life spain in Drosophila. IV. Role of cell size and cell number in the biphasic relationship between life span and growth rate. Mech. Ageing Dev. 1985. Vol. 32, No. 2–3. P. 193–204. doi: 10.1016/0047-6374(85)90079-X.

Shenoi V.N., Syed Z.A., Prasad N.G. Evolution of increased adult longevity in Drosophila melanogaster populations selected for adaptation to larval crowding. J. Evol. Biol. 2016. Vol. 29, No. 2. P. 407–417. doi: 10.1111/jeb.12795.

Martin G.M., Austad S.N., Johnson T.E. Genetic analysis of ageing: role of oxidative damage and environmental stresses. Nature Genetics. 1996. Vol. 13. P. 25–34. doi: 10.1038/ng0596-25.

Buck S., Nicholson M., Dudas S.P., Baker III G.T., Arking R. Larval regulation of adult longevity in a genetically selected long lived strain of Drosophila melanogaster. Heredity. 1993. Vol. 71. P. 23–32. doi: 10.1038/hdy.1993.103.

Sorensen J.G., Loeschcke V. Larval crowding in Drosophila melanogaster induces Hsp70 expression, and leads to increased adult longevity and adult thermal stress resistance. J. Insect. Physiol. 2001. Vol. 47, No. 11. P. 1301–1307. doi: 10.1016/S0022-1910(01)00119-6.

Langley-Evans S.C. Nutrition in early life and the programming of adult disease: a review. J. Hum. Nutr. Diet. 2015. Vol. 28, Suppl 1. P. 1–14. doi: 10.1111/jhn.12212.

Tarry-Adkins J.L., Ozanne S.E. The impact of early nutrition on the ageing trajectory. Proc. Nutr. Soc. 2014. Vol. 73, No. 2. P. 289–301. doi: 10.1017/S002966511300387X.