Genome as a top informational attribute of biological species

  • R. P. Piskun
  • V. M. Shkarupa
  • N. M. Hrynchak
  • O. V. Sprut
  • T. B. Vasenko


Aim. To substantiate a concept of genome as the top informational attribute of biological species based on the modern achievements of biological sciences. Methods. Study and analysis of subject scientific literary sources, in which the technique of genomic analysis is used for determination of a number and similarity of genomes. Results. The main component of genomes is DNA that carries information about the primary structure of proteins (structural genes of matrix RNA), synthesis of proteins (mRNA, tRNA, rRNA), sites for connection of signaling molecules (start/stop expression, amplification, deceleration, repetition, etc.), mobile genetic elements, recombination sites, etc. The genome of each organism has a great variety of genetic nets and systems that control the molecular, biochemical, physiological and morphological features of organisms. At the same time, each gene network has genetic mechanisms designated for its regulation, based on changing functions of certain groups of genes that are part of the gene networks. Conclusions. Therefore, the genome is a part of a cell of a certain living body, consisting of an appropriate set of nucleic acids and proteins, combined into a single structural and functional system.

Keywords: genome, structure, functions.


Russian-Ukrainian Dictionary of Basic Biological and Medical Terms / Editorial board prof. V.S. Picalike. Simferopol, 2004. 328 p.

Medical biology: textbook / ed. VP Pishak, Yu.I. Bajori – Kind. 3rd. Vinnytsya: New Book, 2017. 608 p.

Glazko V.I., Glazko G.V. Introduction to genetics, bioinformatics, DNA technology, gene therapy, DNA-ecology, proteomics, metabolism / Edited by prof. T.T. Eyed. K.: KVIC, 2003. 640 p.

Khesin R.B. Instability of the genome. Moscow: Nauka, 1985. 312 p.

Zhegunov G.F. Laws of Biology. The nature of life. Kharkiv: Consum, 2006. 304 p.

Zhegunov G.F. The Nature of Life and Immortality: Theory, Hypotheses, Philosophy. Kharkov: Espada, 2011. 368 p.

Kulikova N.A., Kovalchuk L.Ye. Medical genetics. Ternopil: Ukrmedkniga, 2004. 188 p.

Ridley M. Genom: Autobiography of the species in 23 chapters [translated from English and edited by cbn. O.N. Revs]. M.: Eksmo, 2008. 432 p.

Kolomyets N.G. Molecular Foundations of Heredity and Variability / Editorial board prof. R.P. Piskun. Vinnitsa: New book. 2005. 144 p.

Wheatley D.N. Cell biology revisited: fifty years of reflection on progress in cell biology. The international symposium on cell biology jointly with 3-rd Ukrainian congress for cell biology: abstract book, (2012, May, 16–20). Yalta, 2012. P. i–ii.

A catalog of genes and hereditary diseases of humans.,Journal of Biological Chemistry/Scientist Serring Scientist/. 2017. URL: http://www.nс (Omim) (Last accesssed: 27.02.2018).